Results for "psoriasis"

...s History Kaposi, 1887 Definition Historical term for a rare, pregnancy-induced variant of pustular psoriasis generalisata. Clinically, there is a usually acute, generalized pustular clinical picture that is i...

...in Pediatr 15: 607-613Shear CS, Nyhan WI, Frost P et al. (1971) Syndromes of unilateral ectromelia, psoriasis, and central nervous system anomalies. Birth Def Orig Art Ser VII: 197-203

...nown, well-standardized index scale (scoring system) for diagnosing and determining the severity of psoriasis. Frequently used in everyday clinical practice to document admission and discharge findings in psor...

Antipsoriatics Definition Agents for the treatment of psoriasis; a distinction is made between agents for external and internal treatment.For external therapy, the...

...not present; 1-4 = present in one or up to 4 quadrants). Note(s) Alternative scores are NPQ10 (Nail Psoriasis Quality of Life) to assess the impact of nail psoriasis on the quality of life of the individual) a...

Balanitis psoriatica Definition Manifestation of psoriasis vulgaris on the glans penis. Clinic Solitary or multiple, sharply delimited, inflammatory reddened,...

Psoriatic form Definition Psoriasiform refers to a skin disease that is associated with psoriasis-like pathological skin changes.

PSORS14 Definition PSORS14 (Psoriasis Susceptibility 14) is a genetic locus associated with psoriasis. PSORS14 is located on chromosome 2...

...ective tissue and supporting apparatus (oligo- or polyarthritis), as a facultative manifestation of psoriasis in the musculoskeletal system. Psoriatic arthritis is characterized by an individual manifestation...

...ody's own regulatory mechanisms and are used to correct dysregulation of the immune system, e.g. in psoriasis, psoriatic arthritis, atopic eczema or urticaria. They intervene in the development of the disease...

PSORS4 Definition PSORS4 (Psoriasis Susceptibility 4) is a genetic locus on chromosome 1q21. Diseases associated with PSORS4 include ps...

...10 and, in therapy responders, interleukin-17A. Indication Moderate and severe forms of plaque-type psoriasis vulgaris in adult patients (in children for severe plaque psoriasis from the 8th year of life) in w...

PSORS7 Definition PSORS7 (PSORS7 stands for Psoriasis Susceptibility 7) is a genetic locus on chromosome 1p. Psoriasis is one of the diseases associated...

...s of the acras. Etiopathogenesis Unresolved; postulated to be a pustular variant of acral localized psoriasis pustulosa palmaris et plantaris. However, only a weak association with psoriasis is found in larger...

...rferons (IFN) as well as their downstream functions. This controls inflammatory processes in plaque psoriasis. Deucravacitinib is approved for the treatment of psoriasis.Tyrosine kinase 2 plays both a structur...

...unosuppressant in rheumatic diseases.In dermatology, MTX is mainly used in severe therapy-resistant psoriasis (chronic active psoriasis vulgaris, localized and generalized pustular psoriasis, arthropathic psor...

...n is able to suppress this hBD2 overexpression (Kim M et al. 2016). Pathophysiology Adiponectin and psoriasis:Adiponectin, has both anti-inflammatory and insulin sensitivity-enhancing effects. Its role in psor...

HLA-Cw1 Definition Psoriasis is a multifactorial disease with a strong genetic background. HLA-Cw6 is one of the most strongly a...

HLA-Cw6 Definition HLA-Cw6 is one of the most strongly associated psoriasis susceptibility alleles. It has been repeatedly observed that the HLA-Cw6 allele influences disease...

...(see interleukins below), which is overexpressed in the pathogenesis of psoriatic inflammation (see psoriasis below) and plays a central role (see Th17 cell). The active ingredient is used in the treatment of...

...omeSystemic sclerodermaVitiligo (Abenavoli L et al. (2019) Lichen sclerosusPemphigusAutoinflammatoryPsoriasisPityriasis rubra pilaris (Randle HW et al.1980)Erythroderma (?)Erythema elevatum diutinumErythema ne...

...to ILK-17RA and IL-17RB. The IL-17 family is involved in the pathogenesis of inflammatory diseases: psoriasis, ulcerative colitis, rheumatoid arthritis, bronchial asthma, lupus erythematosus. The interleukin-1...

...cerbations) in the past in addition to treatment with a bronchodilator drug.Topical roflumilast for psoriasis and seborrheic dermatitis (not previously approved):Psoriasis: Roflumilast, as a selective, potent...

...as inflammatory processes.Mutations of the IL36RN gene are causative for the rare forms of familial psoriasis pustulosa generalisata (PPG). They induce an autoinflammatory enhanced inflammatory response. Such...

...lammatory and selective immunosuppressive effects. Risankizumab is used for the treatment of plaque psoriasis.The effects are based on the binding and inactivation of the cytokine interleukin-23 (IL-23). The r...